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"Paroxysmal cold hemoglobinuria"




  1. Causes and treatments for hemoglobin in urineTreatment
    , it may be due to excessive cold or nocturnal paroxysmal hemoglobinuria, which is a rare type of hemolytic anemia in which there is a change in the red blood cell membrane, which results in itsRead more

Paroxysmal cold hemoglobinuria

Disease

Paroxysmal cold hemoglobinuria (PCH) (also known as Donath-Landsteiner syndrome) is a disease of humans that is characterized by the sudden presence of hemoglobin in the urine (called hemoglobinuria), typically after exposure to cold temperatures.In people with PCH, a polyclonal IgG anti-P autoantibody binds to red blood cell surface antigens in the cold. This can occur in a susceptible...More