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"Hunter syndrome"



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photo Hunter syndrome

Hunter syndrome

Disease

Hunter syndrome, or mucopolysaccharidosis II (MPS II), is a lysosomal storage disease caused by a deficient (or absent) enzyme, iduronate-2-sulfatase (I2S). The accumulated substrates in Hunter syndrome are heparan sulfate and dermatan sulfate. The syndrome has X-linked recessive inheritance.The symptoms of Hunter syndrome (MPS II) are generally not apparent at birth, but usually start to...More